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GHRP-2

Growth Hormone Secretagogue

Price range: $35.00 through $320.00

Quantity

Batch Number :

OPTM2606080462

Purity Percentage :

99.52

Identity Confirmation :

Identity (LC-MS) GHRP-2

Testing Methods Listed :

HPLC with UV detection coupled with mass spectrometry (LC-MS)

Krause Analytical Credential Line :

2606080462

Test Date :

09/06/2026

All products currently listed on this site are for research purposed ONLY.

These products are for laboratory research only and not intended for medical use. They are not FDA-approved to diagnose, treat, cure, or prevent any disease. By purchasing, you certify they will be used solely for research and not for human or animal consumption.

Research Use Only

All research peptides supplied by OPTMZ Peptides are intended strictly for laboratory research applications and are not designed for medical use. These materials are not approved by the U.S. Food and Drug Administration (FDA) to diagnose, treat, cure, or prevent any disease. By purchasing, the buyer confirms use strictly for scientific research purposes and not for human or animal consumption.

Product Overview

GHRP-2, also known as Pralmorelin or KP-102, is a synthetic hexapeptide growth hormone secretagogue investigated in controlled experimental and clinical research for its interaction with the growth hormone secretagogue receptor, also known as the ghrelin receptor (GHSR/GHS-R1a).

GHRP-2 has the sequence D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂ and belongs to the synthetic growth hormone-releasing peptide family. Research has examined its effects on pituitary growth-hormone secretion, ghrelin-receptor signaling, endocrine physiology, food-intake models, and peptide structure-function relationships.

Technical Specifications

  • Product: GHRP-2
  • Quantity: 5 mg label claim
  • Research Classification: Growth Hormone Secretagogue
  • Compound Type: Synthetic Hexapeptide / Ghrelin Receptor Agonist
  • Primary Research Target: Growth Hormone Secretagogue Receptor (GHSR / GHS-R1a)
  • Synonyms: Pralmorelin, KP-102, Growth Hormone-Releasing Peptide-2
  • CAS Number: 158861-67-7
  • PubChem CID: 6918245
  • Molecular Formula: C₄₅H₅₅N₉O₆
  • Molecular Weight: 818.0 g/mol
  • Peptide Length: 6 residues
  • Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
  • Purity: 99.52%
  • Identity: Confirmed by LC-MS
  • Measured Net Content: 5.39 mg
  • Appearance: White lyophilized powder
  • Analysis Method: HPLC-UV coupled with LC-MS
  • Endotoxin Replicate 1: Pass
  • Endotoxin Replicate 2: Pass
  • Assay Sensitivity: ≤0.05 EU/mL
  • Lot: G25

The lot-specific purity, identity, net content, appearance, and endotoxin results above come directly from the Freedom Diagnostics COA.

PubChem identifies GHRP-2 as Pralmorelin, with molecular formula C₄₅H₅₅N₉O₆ and molecular weight 818.0 g/mol.

Analytical & Testing

Each tested batch of GHRP-2 undergoes analytical evaluation to verify purity, identity, peptide content, and analytical consistency.

For the submitted OPTMZ Peptides sample, Freedom Diagnostics reported:

  • Identity (LC-MS): GHRP-2 — Confirmed
  • Purity (HPLC-UV): 99.52%
  • Measured Net Content: 5.39 mg
  • Label Claim: 5 mg
  • Appearance: White lyophilized powder
  • Endotoxin Replicate 1: Pass
  • Endotoxin Replicate 2: Pass
  • Assay Sensitivity: ≤0.05 EU/mL
  • Lot: G25
  • Accession #: 2606080462

The laboratory reports HPLC with UV detection coupled with mass spectrometry and states that endotoxin testing was performed using the Limulus Amebocyte Lysate assay in accordance with USP <85>.

The same single-page COA also contains the chromatogram and mass-confirmation spectrum supporting the reported identity analysis.

Handling & Storage

GHRP-2 should be handled by qualified professionals in controlled laboratory environments. Appropriate storage conditions should be maintained to preserve peptide stability and structural integrity.

Avoid unnecessary exposure to heat, moisture, light, and repeated temperature fluctuations. Experimental preparation, storage, and handling should follow validated laboratory procedures appropriate to the intended research application.

Research Context

GHRP-2 is investigated primarily in experimental and clinical research involving growth hormone secretagogue receptor signaling and pituitary growth-hormone release.

Research areas include:

  • GHSR / ghrelin receptor signaling
  • Growth hormone secretion
  • Pituitary somatotroph biology
  • GH secretagogue pharmacology
  • Ghrelin-mimetic research
  • Appetite and food-intake models
  • Endocrine signaling
  • Gastrointestinal physiology
  • Peptide structure-function studies
  • Comparative growth-hormone secretagogue research

GHRP-2 is a synthetic agonist of the ghrelin receptor and has been extensively studied as a growth hormone secretagogue. Human research has also examined its effects on food intake and circulating GH.

Experimental pituitary-cell research has shown that GHRP-2 can stimulate GH release through a mechanism distinct from direct GHRH receptor activation.

These findings describe experimental and clinical research observations and do not establish approved therapeutic use of the research material supplied here.

Research Application Scope

GHRP-2 is relevant to controlled investigations involving ghrelin-receptor biology, pituitary signaling, growth-hormone secretion, appetite-associated pathways, endocrine pharmacology, and synthetic peptide structure-function relationships.

Because GHRP-2 acts primarily through GHSR, it is mechanistically distinct from GHRH analogs such as Tesamorelin and CJC-1295, which act through the GHRH receptor.

Use Statement

For laboratory research use only. Intended strictly for in vitro and controlled experimental research applications.

Disclaimer

All products currently listed on this site are for research purposes ONLY.

Description

Technical Specifications

  • Product: GHRP-2
  • Quantity: 5 mg label claim
  • Research Classification: Growth Hormone Secretagogue
  • Compound Type: Synthetic Hexapeptide / Ghrelin Receptor Agonist
  • Primary Research Target: Growth Hormone Secretagogue Receptor (GHSR / GHS-R1a)
  • Synonyms: Pralmorelin, KP-102, Growth Hormone-Releasing Peptide-2
  • CAS Number: 158861-67-7
  • PubChem CID: 6918245
  • Molecular Formula: C₄₅H₅₅N₉O₆
  • Molecular Weight: 818.0 g/mol
  • Peptide Length: 6 residues
  • Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂
  • Purity: 99.52%
  • Identity: Confirmed by LC-MS
  • Measured Net Content: 5.39 mg
  • Appearance: White lyophilized powder
  • Analysis Method: HPLC-UV coupled with LC-MS
  • Endotoxin Replicate 1: Pass
  • Endotoxin Replicate 2: Pass
  • Assay Sensitivity: ≤0.05 EU/mL
  • Lot: G25

The lot-specific purity, identity, net content, appearance, and endotoxin results above come directly from the Freedom Diagnostics COA.

PubChem identifies GHRP-2 as Pralmorelin, with molecular formula C₄₅H₅₅N₉O₆ and molecular weight 818.0 g/mol.

Analytical & Testing

Each tested batch of GHRP-2 undergoes analytical evaluation to verify purity, identity, peptide content, and analytical consistency.

For the submitted OPTMZ Peptides sample, Freedom Diagnostics reported:

  • Identity (LC-MS): GHRP-2 — Confirmed
  • Purity (HPLC-UV): 99.52%
  • Measured Net Content: 5.39 mg
  • Label Claim: 5 mg
  • Appearance: White lyophilized powder
  • Endotoxin Replicate 1: Pass
  • Endotoxin Replicate 2: Pass
  • Assay Sensitivity: ≤0.05 EU/mL
  • Lot: G25
  • Accession #: 2606080462

The laboratory reports HPLC with UV detection coupled with mass spectrometry and states that endotoxin testing was performed using the Limulus Amebocyte Lysate assay in accordance with USP <85>.

The same single-page COA also contains the chromatogram and mass-confirmation spectrum supporting the reported identity analysis.

Handling & Storage

GHRP-2 should be handled by qualified professionals in controlled laboratory environments. Appropriate storage conditions should be maintained to preserve peptide stability and structural integrity.

Avoid unnecessary exposure to heat, moisture, light, and repeated temperature fluctuations. Experimental preparation, storage, and handling should follow validated laboratory procedures appropriate to the intended research application.

Research Context

GHRP-2 is investigated primarily in experimental and clinical research involving growth hormone secretagogue receptor signaling and pituitary growth-hormone release.

Research areas include:

  • GHSR / ghrelin receptor signaling
  • Growth hormone secretion
  • Pituitary somatotroph biology
  • GH secretagogue pharmacology
  • Ghrelin-mimetic research
  • Appetite and food-intake models
  • Endocrine signaling
  • Gastrointestinal physiology
  • Peptide structure-function studies
  • Comparative growth-hormone secretagogue research

GHRP-2 is a synthetic agonist of the ghrelin receptor and has been extensively studied as a growth hormone secretagogue. Human research has also examined its effects on food intake and circulating GH.

Experimental pituitary-cell research has shown that GHRP-2 can stimulate GH release through a mechanism distinct from direct GHRH receptor activation.

These findings describe experimental and clinical research observations and do not establish approved therapeutic use of the research material supplied here.

Research Application Scope

GHRP-2 is relevant to controlled investigations involving ghrelin-receptor biology, pituitary signaling, growth-hormone secretion, appetite-associated pathways, endocrine pharmacology, and synthetic peptide structure-function relationships.

Because GHRP-2 acts primarily through GHSR, it is mechanistically distinct from GHRH analogs such as Tesamorelin and CJC-1295, which act through the GHRH receptor.

Use Statement

For laboratory research use only. Intended strictly for in vitro and controlled experimental research applications.

Disclaimer

All products currently listed on this site are for research purposes ONLY.

Additional information

Pcs

Single Vial, Pack of 10

Strength

10mg

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Research Profile

Research Classification

Growth Hormone Secretagogue / Ghrelin Receptor Agonist

Research Discipline

Endocrinology; Peptide Biology; Ghrelin Receptor Research; Pituitary Biology; Metabolic Research; Gastrointestinal Physiology

Primary Molecular Target

Growth Hormone Secretagogue Receptor (GHSR / GHS-R1a), also known as the ghrelin receptor GHRP-2 is described in published human research as a synthetic ghrelin agonist acting through the growth hormone secretagogue receptor.

Evidence Level

Clinical Research GHRP-2 has been evaluated in controlled human studies in addition to substantial preclinical research. Human investigations have examined GH secretion, appetite, and food intake. This classification refers to the existence of human research and does not imply FDA approval or established therapeutic efficacy.

Molecular Structure

GHRP-2 is a synthetic six-residue growth hormone secretagogue incorporating several non-natural amino-acid residues. Its sequence is D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂, including D-alanine, D-2-naphthylalanine, and D-phenylalanine residues. These structural modifications distinguish GHRP-2 from endogenous peptide hormones and contribute to its utility as an experimental GHSR agonist.

Chemical Identity

Molecular FormulaC₄₅H₅₅N₉O₆
Molecular Weight818.0 g/mol
CAS Number158861-67-7 PubChem substance records associate this CAS number with GHRP-2 / Pralmorelin.

Amino Acid Sequence

158861-67-7 PubChem substance records associate this CAS number with GHRP-2 / Pralmorelin.

Experimental Research Applications

GHSR receptor signaling studies
Growth hormone secretion research
Pituitary somatotroph research
Ghrelin-receptor pharmacology
Appetite and food-intake research
Endocrine signaling studies
Gastrointestinal physiology research
GH secretagogue comparisons
Peptide structure-function research
Growth hormone pathway analysis

Experimental Systems

Rat pituitary-cell cultures
Pituitary somatotroph systems
Human endocrine studies
Human food-intake studies
Ghrelin-receptor signaling models
Gastrointestinal physiology models
Growth hormone response models
Experimental systems with altered GHRH receptor signaling

Human studies have examined both GH release and food-intake responses to GHRP-2.

Specific Assays

HPLC-UV purity analysis
LC-MS identity confirmation
Mass-spectral analysis
LAL endotoxin assay
Serum growth hormone assays
GH secretion assays
GHSR signaling assays
Pituitary-cell GH-release assays
Food-intake measurement
Endocrine hormone profiling
Gastrointestinal motility assays
Receptor-signaling studies

For the actual OPTMZ lot, the COA specifically documents HPLC-UV, LC-MS, and USP LAL endotoxin testing.

Measured Endpoints

Chromatographic purity
Peptide identity
Net peptide content
Endotoxin assay result
Growth hormone concentration
GH secretory response
GHSR-associated signaling
Food intake
Appetite-associated responses
Pituitary-cell activity
Gastrointestinal physiological responses

For the actual OPTMZ product, the directly measured analytical endpoints were purity, identity, GHRP-2 content, appearance, and endotoxin assay performance.

Analytical Characterization

Independent analytical testing of OPTMZ Peptides GHRP-2 5 mg, lot G25, by Freedom Diagnostics reported:

Purity (HPLC-UV): 99.52%
Identity (LC-MS): GHRP-2 confirmed
Measured Net Content: 5.39 mg
Label Claim: 5 mg
Appearance: White lyophilized powder
Endotoxin Replicate 1: Pass
Endotoxin Replicate 2: Pass
Assay Sensitivity: ≤0.05 EU/mL
Analytical Method: HPLC with UV detection coupled with LC-MS
Endotoxin Method: Limulus Amebocyte Lysate assay in accordance with USP
Accession #: 2606080462
Date Received: June 8, 2026
Report Issued: June 9, 2026

These results come directly from the Freedom Diagnostics Certificate of Analysis for the submitted lot.

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